Blastic Natural Killer Cell Lymphoma/Leukemia
نویسندگان
چکیده
منابع مشابه
Primary cutaneous blastic natural killer cell lymphoma.
Sir, Blastic natural killer-cell lymphoma, also called “agranular CD4+ CD56+ haematodermic neoplasm” is an uncommon type of tumour, which is included in the new World Health Organization (WHO) classification as a malignancy derived from natural killer (NK) cells. It is very aggressive, affecting many organs, and skin involvement is highly characteristic. Several origins have been proposed, but ...
متن کاملBlastic natural killer (NK) cell leukemia (agranular CD4+CD56+ leukemia).
Blastic NK cell lymphoma is a rare hematolymphoid neoplasm. This report illustrates an unusual presentation of this entity, namely as a primary leukemia, but without skin lesions.
متن کاملBlastic CD56+ natural killer-cell lymphoma with primary cutaneous manifestation.
T/natural killer-cell lymphomas belong to a heterogeneous group of non-Hodgkin lymphomas with predominant extranodal, often cutaneous, manifestations. In contrast to B- and T-cell lymphomas, T/NK-cell lymphomas were only recently regarded as a distinct entity. These rather aggressive malignancies arise from cytotoxic T cells, NK-cells or NK-like T cells, which share several phenotypic and funct...
متن کاملNatural killer cell deficiency.
Natural killer (NK) cells are part of the innate immune defense against infection and cancer and are especially useful in combating certain viral pathogens. The utility of NK cells in human health has been underscored by a growing number of persons who are deficient in NK cells and/or their functions. This can be in the context of a broader genetically defined congenital immunodeficiency, of wh...
متن کاملNatural killer cell neoplasms.
Lymphoid neoplasms that are derived from natural killer (NK) cells are uncommon but distinct clinicopathologic disease entities. Three types have been recognized and categorized in the latest World Health Organization classification: extranodal NK cell lymphoma, nasal-type; aggressive NK cell leukemia; and blastic NK cell lymphoma. All NK tumor cells express the NK cell marker CD56, but they la...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2002
ISSN: 0002-9173,1943-7722
DOI: 10.1309/uuxv-yrl8-gxp7-hr4h